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FGFR1 inhibitor-18

FGFR1 inhibitor-18 (compound 16) is a potent FGFR1 inhibitor with an IC50 value of 1.31 nM. FGFR1 inhibitor-18 can occupy within the ATP-binding pocket of the target FGFR1[1].

Product Specifications

UNSPSC

12352005

Target

FGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C1C(Cl)=C(NC2=CC(C3=CN(C4=CC=C(C(C)=O)C=C4)N=N3)=CC=C2)C(C5=CC=CC=C51)=O

Molecular Formula

C26H17ClN4O3

Molecular Weight

468.89

References & Citations

[1]Ronnakorn Leechaisit, et al. Design, Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel Naphthoquinone-Triazole Hybrids as Potential FGFR1 Tyrosine Kinase Inhibitors. Asian Journal of Organic Chemistry, 2025: e202400813.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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