FGFR1 inhibitor-18
FGFR1 inhibitor-18 (compound 16) is a potent FGFR1 inhibitor with an IC50 value of 1.31 nM. FGFR1 inhibitor-18 can occupy within the ATP-binding pocket of the target FGFR1[1].
Product Specifications
UNSPSC
12352005
Target
FGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C1C(Cl)=C(NC2=CC(C3=CN(C4=CC=C(C(C)=O)C=C4)N=N3)=CC=C2)C(C5=CC=CC=C51)=O
Molecular Formula
C26H17ClN4O3
Molecular Weight
468.89
References & Citations
[1]Ronnakorn Leechaisit, et al. Design, Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel Naphthoquinone-Triazole Hybrids as Potential FGFR1 Tyrosine Kinase Inhibitors. Asian Journal of Organic Chemistry, 2025: e202400813.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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