AR antagonist 13

AR antagonist 13 (compound 19) is an androgen receptor antagonist with inhibition rates exceeding 71.5% at 10 μM. AR antagonist 13 inhibits prostate cancer cell growth[1].

Product Specifications

UNSPSC

12352005

Target

Androgen Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC1=CC=CC=C1OCCC2=CC=C(CN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)C=C2

Molecular Formula

C33H36N2O

Molecular Weight

476.65

References & Citations

[1]Jiang H, et al. Synthesis, bioactivity, and molecular docking studies: novel arylpiperazine derivatives as potential new-resistant AR antagonists. Front Chem. 2025 Mar 28;13:1557275.