Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is a tubulin polymerization inhibitor with an IC50 value of 2.69 μM. Tubulin polymerization-IN-78 shows antiproliferative activity[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
O=C(NC1=NC(C2=CC=CC=C2)=CS1)CSC3=NC(C)=C(C(/C=C/C4=CC=CC=C4)=O)S3
Molecular Formula
C24H19N3O2S3
Molecular Weight
477.62
References & Citations
[1]Al-Wahaibi LH, et al. Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors. Front Chem. 2025 Apr 16;13:1565699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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