SL-176

SL-176, a WIP1 inhibitor, induces cell cycle arrest and apoptosis when combined with GSK-J4 (HY-15648B), thereby suppressing tumor growth both in vitro and in vivo[1].

Product Specifications

CAS Number

[1809556-48-6]

UNSPSC

12352211

Target

Apoptosis; Phosphatase

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

CC[Si](CC)(CC)O[C@@H]1CCC[C@@]2([H])[C@@](C(O)=O)(C)C[C@@H](O[Si](C)(C(C)(C)C)C)C[C@@]21[H]

Molecular Formula

C24H48O4Si2

Molecular Weight

456.81

References & Citations

[1]Treis D, et al. Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth. Cell Death Dis. 2025 Apr 19;16 (1) :318.