TNF-α-IN-24
TNF-α-IN-24 (Example 15) is a TNF-α inhibitor with an IC50 of 4.1 nM. TNF-α-IN-24 can be used in study of inflammatory and autoimmune disorders such as rheumatoid arthritis and Crohn’s disease[1].
Product Specifications
CAS Number
3075686-66-4
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Smiles
CN([C@H]1C2=NN(C=CC(C3=CN=C(C4(CCC4)N)N=C3)=C5)C5=C2[C@@H](C6=C(OC(F)F)C=CC=C67)C1)C7=O
Molecular Formula
C27H24F2N6O2
Molecular Weight
502.52
References & Citations
[1]Pengyu YANG, et al. Modulators of tnf alpha activity and uses thereof. WO2025038927A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
1350-AAT 2 Labelings
Buccutite™ Rapid APC-Cy5.5 Tandem Antibody Labeling Kit *Microscale Optimized for Labeling 25 ug Antibody Per Reaction*
Sign In for Pricing
View Details 
