TNF-α-IN-24
TNF-α-IN-24 (Example 15) is a TNF-α inhibitor with an IC50 of 4.1 nM. TNF-α-IN-24 can be used in study of inflammatory and autoimmune disorders such as rheumatoid arthritis and Crohn’s disease[1].
Product Specifications
CAS Number
[3075686-66-4]
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Smiles
CN([C@H]1C2=NN(C=CC(C3=CN=C(C4(CCC4)N)N=C3)=C5)C5=C2[C@@H](C6=C(OC(F)F)C=CC=C67)C1)C7=O
Molecular Formula
C27H24F2N6O2
Molecular Weight
502.52
References & Citations
[1]Pengyu YANG, et al. Modulators of tnf alpha activity and uses thereof. WO2025038927A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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