Neuroprotective agent 10
Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective agent. Neuroprotective agent 10 scavenges ABTS radicals (scavenging IC50: 9.20 μM), DPPH radicals (scavenging IC50: 7.09 μM) and superoxide anion radicals (inhibition percentage: 48.4%) . Neuroprotective agent 10 also alleviates H2O2-induced oxidative damage and LPS-induced neuroinflammation with antiepileptic activity. Neuroprotective agent 10 is promising for research of epilepsy and neuroprotection[1].
Product Specifications
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
OC1=C(OC)C=C(CNCCCN2CCCC(C(N)=O)C2)C=C1
Molecular Formula
C17H27N3O3
Molecular Weight
321.41
References & Citations
[1]Li W, et al. Design, synthesis and biological evaluation of N-substituted nipecotamide derivatives as multifunctional agents for epilepsy treatment. Eur J Med Chem. 2025 Apr 10;292:117613.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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