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Apoptosis inducer 48

Apoptosis inducer 48 (5d) is an apoptotic agent. Apoptosis inducer 48 inhibits the growth of triple-negative breast cancer cells. Apoptosis inducer 48 attenuates proteasomal degradation via the ubiquitin-proteasome pathway, leading to G2/M phase cell cycle arrest and the induction of apoptotic[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; E1/E2/E3 Enzyme

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1/C(CN(C2CC2)C/C1=C\C3=CC=C(O)C(OC)=C3)=C/C4=CC=CC=C4

Molecular Formula

C23H23NO3

Molecular Weight

361.43

References & Citations

[1]Khor PY, et al. Discovery of New Non-Symmetrical Heterocyclic Pentanoid Derivatives Targeting Metastatic Triple-Negative Breast Cancer. Bioorg Med Chem Lett. 2025 Aug 1;123:130232.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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