Apoptosis inducer 48
Apoptosis inducer 48 (5d) is an apoptotic agent. Apoptosis inducer 48 inhibits the growth of triple-negative breast cancer cells. Apoptosis inducer 48 attenuates proteasomal degradation via the ubiquitin-proteasome pathway, leading to G2/M phase cell cycle arrest and the induction of apoptotic[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; E1/E2/E3 Enzyme
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1/C(CN(C2CC2)C/C1=C\C3=CC=C(O)C(OC)=C3)=C/C4=CC=CC=C4
Molecular Formula
C23H23NO3
Molecular Weight
361.43
References & Citations
[1]Khor PY, et al. Discovery of New Non-Symmetrical Heterocyclic Pentanoid Derivatives Targeting Metastatic Triple-Negative Breast Cancer. Bioorg Med Chem Lett. 2025 Aug 1;123:130232.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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