GABAA receptor modulator-7
GABAA receptor modulator-7 (compound 1m), a spiro-Barbiturate, is a GABAA receptor modulator. GABAA receptor modulator-7 reverses the action of anesthetics without affecting GABA-induced desensitization and can be used for study of antiepileptics and anxiolytics[1].
Product Specifications
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1(C(N2)=O)CCC3=C1C=CC=C3)NC2=N.Cl
Molecular Formula
C12H12ClN3O2
Molecular Weight
265.70
References & Citations
[1]Koinas D, et al. Novel Spiro-Barbiturates Can Reverse the Action of General Anesthetics on the GABAAR. J Med Chem. 2025 Apr 24;68 (8) :8025-8045.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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