Kv7.2/Kv7.3 modulator-2
Kv7.2/Kv7.3 modulator-2 (compound 7d) is a Kv7.2/Kv7.3 modulator with the pEC50 of 7.42 (KV7.2/3 channel opening activity) . Kv7.2/Kv7.3 modulator-2 can be used for study of epilepsy, depression, brain injury and pain[1].
Product Specifications
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC1=C(C(NCC2=CC=C(F)C=C2)=O)C(OC(C)C)=NC(N3[C@H]4COC[C@@H]3CC4)=C1
Molecular Formula
C23H28FN3O3
Molecular Weight
413.49
References & Citations
[1]Lemke J, et al. Lead Optimization of Positive Allosteric KV7.2/3 Channel Modulators toward Improved Balance of Lipophilicity and Aqueous Solubility. J Med Chem. 2025 Apr 24;68 (8) :8377-8399.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172585/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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