Kv7.2/Kv7.3 modulator-1
Kv7.2/Kv7.3 modulator-1 (compound 6a) is a Kv7.2/Kv7.3 modulator with the pEC50 of 7.96 (KV7.2/3 channel opening activity) . Kv7.2/Kv7.3 modulator-1 can be used for study of epilepsy, depression, brain injury and pain[1].
Product Specifications
CAS Number
2981435-42-9
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC1=C(C(NCC2=CC=C(F)C=C2)=O)C(OCC(F)(F)F)=NC(N3CCOCC3)=C1
Molecular Formula
C20H21F4N3O3
Molecular Weight
427.39
References & Citations
[1]Lemke J, et al. Lead Optimization of Positive Allosteric KV7.2/3 Channel Modulators toward Improved Balance of Lipophilicity and Aqueous Solubility. J Med Chem. 2025 Apr 24;68 (8) :8377-8399.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470043-500 1x 500 µL
P21 / WAF1 (WA-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682848-500 1x 500 µL
Fibronectin (Fn-3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471060-100 1x 100 µL
Chromogranin A (CGA414 + CGA/777 + CGA/798), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details