CDK9-IN-38
CDK9-IN-38 (compound 14) is a CDK9 inhibitor with IC50 values of 1.2 nM and 3.3 nM for CDK9 wild-type and L156F mutant, respectively. CDK9-IN-38 inhibits tumor growth in vivo and in vitro[1].
Product Specifications
CAS Number
[2773402-44-9]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1NCC(C)(C)C2=CC(C3=NC(NC4=CC=CC(CS(N)(=O)=O)=C4)=NC=C3)=CC=C21
Molecular Formula
C22H23N5O3S
Molecular Weight
437.51
References & Citations
[1]Shi C, et al. Discovery of a Novel Dihydroisoquinolinone Derivative as a Potent CDK9 Inhibitor Capable of Overcoming L156F Mutant for the Treatment of Hematologic Malignancies. J Med Chem. 2025 Apr 24;68 (8) :8106-8123.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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