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PLC thio-PIP2 (trisodium)

PLC thio-PIP2 trisodium is an analog of naturally occurring PIP2. PLC thio-PIP2 trisodium can simulate the process of PIP2 being hydrolyzed by PLC in in vitro experiments, and then quantitatively analyze the activity of PLC by detecting the free thiol produced by hydrolysis[1].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

CCCCCC(OC[C@H](CSP(O[C@@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(O)(O[Na])=O)OP(O)(O[Na])=O)O)O)(O[Na])=O)OC(CCCCC)=O)=O

Molecular Formula

C21H38Na3O18P3S

Molecular Weight

772.47

References & Citations

[1]Liu K, et al. Germline Mutation of PLCD1 Contributes to Human Multiple Pilomatricomas through Protein Kinase D/Extracellular Signal-Regulated Kinase1/2 Cascade and TRPV6. J Invest Dermatol. 2021 Mar;141 (3) :533-544.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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