Posaconazole D-glucuronide

Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is a glucuronide metabolite of the antifungal agent Posaconazole (HY-17373) . Posaconazole D-glucuronide can be formed in human liver microsomes catalyzed by UGT1A4[1].

Product Specifications

Product Name Alternative

SCH 56592 D-glucuronide

UNSPSC

12352005

Target

Drug Metabolite; UGT

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C1N(N=CN1C2=CC=C(N3CCN(CC3)C4=CC=C(C=C4)OC[C@@H]5CO[C@@](C6=CC=C(C=C6F)F)(C5)CN7C=[N+](C=N7)[C@]8([C@@H]([C@H]([C@@H]([C@H](O8)C([O-])=O)O)O)O)[H])C=C2)[C@@H](CC)[C@H](C)O

Molecular Formula

C43H50F2N8O10

Molecular Weight

876.90

References & Citations

[1]Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme (s) responsible for the glucuronidation of posaconazole (Noxafil) . Drug Metab Dispos. 2004 Feb;32 (2) :267-71.