Posaconazole D-glucuronide
Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is a glucuronide metabolite of the antifungal agent Posaconazole. Posaconazole D-glucuronide can be formed in human liver microsomes catalyzed by UGT1A4[1].
Product Specifications
Product Name Alternative
SCH 56592 D-glucuronide
UNSPSC
12352005
Target
Drug Metabolite; UGT
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C1N(N=CN1C2=CC=C(N3CCN(CC3)C4=CC=C(C=C4)OC[C@@H]5CO[C@@](C6=CC=C(C=C6F)F)(C5)CN7C=[N+](C=N7)[C@]8([C@@H]([C@H]([C@@H]([C@H](O8)C([O-])=O)O)O)O)[H])C=C2)[C@@H](CC)[C@H](C)O
Molecular Formula
C43H50F2N8O10
Molecular Weight
876.90
References & Citations
[1]Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme (s) responsible for the glucuronidation of posaconazole (Noxafil) . Drug Metab Dispos. 2004 Feb;32 (2) :267-71.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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