BTR2000-Gly-Gly-Gly
BTR2000-Gly-Gly-Gly is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004 (HY-172562) [1].
Product Specifications
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NCC(NCC(NCC(N[C@H](C(N1[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CSC2)=O)=O)=O)CCC1)=O)CSCC3=CC=CC2=C3)=O)=O)=O
Molecular Formula
C35H51N9O10S2
Molecular Weight
821.96
References & Citations
[1]Phoebe H Fechtmeyer, et al. Temporal and Spatial Characterization of CUL3KLHL20-driven Targeted Degradation of BET family, BRD Proteins by the Macrocycle-based Degrader BTR2004. bioRxiv [Preprint]. 2024 Dec 7:2024.12.07.627262.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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