CFTR corrector 18
CFTR corrector 18 (Compound I-99) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. CFTR corrector 18 facilitates the processing and trafficking of CFTR, increasing the number of CFTR on the cell surface. CFTR corrector 18 is promising for research of cystic fibrosis (CF) [1].
Product Specifications
CAS Number
[2993441-49-7]
UNSPSC
12352005
Target
CFTR
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Endocrinology
Smiles
CC(C)(C)C1=CC2=NC(CN(C(C3=CC(S(=O)(NC4=NC(C5=C(C=CC=C5C)C)=CC(OC6)=N4)=O)=CC=C3)=O)[C@@H]6CC78CC(C8)C7)=CN=C2O1
Molecular Formula
C38H40N6O5S
Molecular Weight
692.83
References & Citations
[1]Alexander Russell Abela, et al. Modulators of cystic fibrosis transmembrane conductance regulator. WO2023196429A1. 2023-10-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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