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TTBK1/2-IN-1

TTBK1/2-IN-1 (compound 3) is a potent Tau tubulin kinase 1 (TTBK1) and TTBK2 inhibitor with IC50s of 816 nM and 384 nM, respectively[1].

Product Specifications

CAS Number

[2342571-09-7]

UNSPSC

12352005

Target

Tau Protein

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

NC1=NC=CC(C2=CNC3=C2C=C(C#CC(C)(O)C)C=C3)=N1

Molecular Formula

C17H16N4O

Molecular Weight

292.34

References & Citations

[1]Bashore FM, et al. Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. Sci Rep. 2023 Apr 14;13 (1) :6118.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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