Lipid OA2 (dihydrochloride)
Lipid OA2 dihydrochloride is an ionizable cationic lipid that can be used to prepare single-component lipid nanoparticles for siRNA delivery. Lipid OA2 dihydrochloride can effectively deliver SOCS1-siRNA to dendritic cells, silence the SOCS1 gene, and enhance their antigen-presenting ability and pro-inflammatory factor secretion capacity[1].
Product Specifications
UNSPSC
12352211
Target
Lipase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
NCCCC[C@H](N)C(N[C@H](C(OCCCCCCCC/C=C\CCCCCCCC)=O)CCC(OCCCCCCCC/C=C\CCCCCCCC)=O)=O.Cl.Cl
Molecular Formula
C47H91Cl2N3O5
Molecular Weight
849.15
References & Citations
[1]Yu Z, et al. Single-component lipid nanoparticles for engineering SOCS1 gene-silenced dendritic cells to boost tumor immunotherapy. Biomater Sci. 2022 Dec 20;11 (1) :263-277.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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