4A3-SCC-10
4A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection[1].
Product Specifications
CAS Number
[3082361-42-7]
UNSPSC
12352100
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Concentration
5.13 mM * 500 μL in Ethanol
Purity
94.4
Smiles
CN(CCCN(CCC(OCCSSCCOC(C(C)CSCCCCCCCCCC)=O)=O)CCC(OCCSSCCOC(C(C)CSCCCCCCCCCC)=O)=O)CCCN(CCC(OCCSSCCOC(C(C)CSCCCCCCCCCC)=O)=O)CCC(OCCSSCCOC(C(CSCCCCCCCCCC)C)=O)=O
Molecular Formula
C91H171N3O16S12
Molecular Weight
1948.12
References & Citations
[1]Chen Z, Tian Y, et al. Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo. J Am Chem Soc. 2023 Nov 8;145 (44) :24302-24314.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Curated Selection
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