CDA-IN-3

CDA-IN-3 (NCDI) is an inhibitor of chitin deacetylase (CDA) with anti-parasitic activity. CDA-IN-3 disrupts the chitin metabolism of nematodes, leading to an increase in the level of ROS in nematodes and causing cell damage. CDA-IN-3 has a significant inhibitory effect on all developmental stages of Caenorhabditis elegans. CDA-IN-3 can be used in the research of the anti-infection field [1].

Product Specifications

CAS Number

[932889-57-1]

UNSPSC

12352005

Target

Fungal; Parasite; Reactive Oxygen Species (ROS)

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Infection

Smiles

O=C(NCCSC(C)(C)C)CN(S(=O)(N(C)C)=O)C1=CC=CC=C1

Molecular Formula

C16H27N3O3S2

Molecular Weight

373.53

References & Citations

[1]Galvez-Llompart M, et al. Rational Design of a Potential New Nematicide Targeting Chitin Deacetylase. J Agric Food Chem. 2024 Feb 7;72 (5) :2482-2491.