(1R,2S,3R) -Aprepitant
(1R,2S,3R) -Aprepitant (Compound ent-4) is a competitive human neurokinin-1 (NK-1) receptor antagonist. (1R,2S,3R) -Aprepitant is promising for research of cancers and postoperative nausea and vomiting[1].
Product Specifications
UNSPSC
12352005
Target
Neurokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer
Smiles
C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)O[C@H](OCC2)[C@@H](C3=CC=C(C=C3)F)N2CC4=NNC(N4)=O
Molecular Formula
C23H21F7N4O3
Molecular Weight
534.43
References & Citations
[1]Kulangiappar K, et al. Synthetic communications: an international journal for rapid communication of synthetic organic chemistry[J]. Synthetic Communications, 2014, 1 (44) : 2494-2502.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172514/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[1185502-97-9]
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