DSPE-PEG3400-iRGD
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD) . iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery[1].
Product Specifications
UNSPSC
12352200
Target
Integrin; Liposome
Related Pathways
Cytoskeleton; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[CRGDKGPDC(Disulfidebridge:Cys1-Cys9)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
Molecular Weight
3400 (Average)
References & Citations
[1]Puig-Saus C, et al. iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy. Gene Ther. 2014 Aug;21 (8) :767-74.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
138331-Biotin 100 µL
SDF4 (45kD Calcium-binding Protein, Cab45, Stromal Cell-derived Factor 4, SDF-4, CAB45, PSEC0034) (Biotin)
Ask
View Details 500361 10 µg
PI3K, p110 alpha, p55 gamma, Recombinant, Human, His-Tag (Phosphatidylinositol 3-Kinase) discontinued
Ask
View Details 
