DSPE-PEG5000-K237

DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237) . K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery[1].

Product Specifications

UNSPSC

12352200

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[Mal-Cys-HTMYYHHYQHHL]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

Molecular Weight

5000 (Average)

References & Citations

[1]Hetian L, et al. A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor. J Biol Chem. 2002 Nov 8;277 (45) :43137-42.