Mtb-IN-11
Mtb-IN-11 (Compound 1e) is an inhibitor of Mycobacterium tuberculosis salicylate synthase (MbtI), with an IC50 of 11.2 μM. Mtb-IN-11 exhibits good in vitro anti-tuberculosis activity, with a MIC99 of 32 μM against M. bovis BCG. Mtb-IN-11 can be used for the research of tuberculosis[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(C#N)=C2)O1)O
Molecular Formula
C16H15NO4
Molecular Weight
285.29
References & Citations
[1]Cazzaniga G, et al. Nanoenabling MbtI Inhibitors for Next-Generation Tuberculosis Therapy. J Med Chem. 2025 Mar 13;68 (5) :5312-5332.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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