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Mtb-IN-11

Mtb-IN-11 (Compound 1e) is an inhibitor of Mycobacterium tuberculosis salicylate synthase (MbtI), with an IC50 of 11.2 μM. Mtb-IN-11 exhibits good in vitro anti-tuberculosis activity, with a MIC99 of 32 μM against M. bovis BCG. Mtb-IN-11 can be used for the research of tuberculosis[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(C#N)=C2)O1)O

Molecular Formula

C16H15NO4

Molecular Weight

285.29

References & Citations

[1]Cazzaniga G, et al. Nanoenabling MbtI Inhibitors for Next-Generation Tuberculosis Therapy. J Med Chem. 2025 Mar 13;68 (5) :5312-5332.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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