XW-032
XW-032 is an apo-IDO1 inhibitor, with an IC50 of 21 nM. XW-032 (TGI = 63%) exhibits potent in vivo anti-tumor efficacy in the CT26 syngeneic mouse model and is expected to be applied in the research of the field of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(CCCC1=CC=C(C=C1)C2=NC=C(C=C2)F)NC3=CC=C(C=C3)F
Molecular Formula
C21H18F2N2O
Molecular Weight
352.38
References & Citations
[1]Cen L, et al. Discovery and Optimization of Novel Apo-IDO1 Inhibitors by a Pharmacophore-Based Structural Simplification Strategy. J Med Chem. 2025 Mar 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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