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Rocavorexant

Rocavorexant is the antagonist for orexin-1 receptor with pIC50 of 9.1 for human OX1 (while pIC50 for human OX2 is 6.0) [1].

Product Specifications

CAS Number

[2115665-09-1]

UNSPSC

12352005

Target

Orexin Receptor (OX Receptor)

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

FC(F)(F)C1=CN=C(C=N1)NC[C@H](C)N(C)C(C2=C(N3N=CC=N3)C=CC(C)=N2)=O

Molecular Formula

C18H19F3N8O

Molecular Weight

420.39

References & Citations

[1]Martin B, et al. Therapeutic compounds. WO2017129829

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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