Opakalim
Opakalim (BHV-7000) is a selective and orally active Kv7.2/7.3 potassium channels activator. Opakalim shows minimal GABAA receptor activation and exhibits potent anti-seizure efficacy in the maximal electroshock seizure (MES) model. Opakalim can be used for the study of seizures[1].
Product Specifications
CAS Number
2376397-93-0
Product Name Alternative
BHV-7000
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.88
Smiles
N#CC1=C(F)C2=C(N=C(N2C(C)(C)C)NC(CC(C)(C)C)=O)C(F)=C1
Molecular Formula
C18H22F2N4O
Molecular Weight
348.39
References & Citations
[1]WHO-Volume38 Number4 2024|[2]Bharat Awsare, et al. Phase 1 Study Evaluating the Safety and Tolerability of BHV-7000, a Novel, Selective Kv7.2/7.3 Potassium Channel Activator, in Healthy Adults (P8-1.007) . April 9, 2024 issue.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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