Opakalim

Opakalim (BHV-7000) is a selective and orally active Kv7.2/7.3 potassium channels activator. Opakalim shows minimal GABAA receptor activation and exhibits potent anti-seizure efficacy in the maximal electroshock seizure (MES) model. Opakalim can be used for the study of seizures[1].

Product Specifications

CAS Number

[2376397-93-0]

Product Name Alternative

BHV-7000

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.88

Smiles

N#CC1=C(F)C2=C(N=C(N2C(C)(C)C)NC(CC(C)(C)C)=O)C(F)=C1

Molecular Formula

C18H22F2N4O

Molecular Weight

348.39

References & Citations

[1]WHO-Volume38 Number4 2024|[2]Bharat Awsare, et al. Phase 1 Study Evaluating the Safety and Tolerability of BHV-7000, a Novel, Selective Kv7.2/7.3 Potassium Channel Activator, in Healthy Adults (P8-1.007) . April 9, 2024 issue.