Epaldeudomide
Epaldeudomide (Compound A406) is the inhibitor for TNF-α (>50% inhibition rate at 100 nM) . Epaldeudomide inhibits the proliferation of cancer cells MM.1S (IC50 IC50 IC50 [1].
Product Specifications
CAS Number
[1918159-31-5]
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
FC(C=C(C=C1)CN2CCOCC2)=C1COC3=C4C(C(N([C@]5([2H])C(NC(CC5)=O)=O)C4)=O)=CC=C3
Molecular Formula
C25H25DFN3O5
Molecular Weight
468.50
References & Citations
[1]Ge C, et al., Isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof. WO2016065980
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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