Encofosbuvir
Encofosbuvir is the inhibitor for HCV NS5B polymerase that inhibits GT1b, GT2a and GT3a with EC50 of 102.4, 82.51 and 46.91 nM. Encofosbuvir inhibits HCV replication and can be used for reseearchs of hepatitis C in mammals[1].
Product Specifications
CAS Number
[2232134-77-7]
UNSPSC
12352005
Target
HCV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C=CN1[C@H]2[C@@](F)(C)[C@H](O)[C@@H](CO[P@@](N[C@@H](C)C(OC(C)C)=O)(OC3=CC=CC=C3)=O)O2)N(COC([C@@H](NC(OC)=O)CCSC)=O)C1=O
Molecular Formula
C30H42FN4O13PS
Molecular Weight
748.71
References & Citations
[1]Zhang Y, et al., Prodrug of antiviral nucleoside analogues, and composition and use thereof. WO2018121678
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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