Alixorexton enantiomer

Alixorexton (ALKS 2680) enantiomer is the enantiomer of Alixorexton (HY-172412) . Alixorexton is a selective, orally active and brain-penetrant agonist for orexin-2 receptor and can be used for hypersomnias research[1].

Product Specifications

CAS Number

[2648350-16-5]

Product Name Alternative

ALKS 2680 enantiomer

UNSPSC

12352005

Target

Orexin Receptor (OX Receptor)

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.42

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N2CCC[C@H]([C@H]2CO[C@@H]3CC[C@@H](CC3)C4=C(OC1)C=CC=C4)NS(=O)(C)=O

Molecular Formula

C21H30N2O5S

Molecular Weight

422.54

References & Citations

[1]B Yee, et al., O013 Preliminary Results from a Phase 1 Study of ALKS 2680, an Orexin-2 receptor Agonist, in Healthy Participants and Patients with Narcolepsy or Idiopathic Hypersomnia.