Alixorexton
Alixorexton (ALKS 2680) is a selective, orally active and brain-penetrant agonist for orexin-2 receptor and can be used for hypersomnias research[1].
Product Specifications
Product Name Alternative
ALKS 2680
UNSPSC
12352005
Target
Orexin Receptor (OX Receptor)
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Purity
99.96
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N2CCC[C@@H]([C@@H]2CO[C@@H]3CC[C@@H](CC3)C4=C(OC1)C=CC=C4)NS(=O)(C)=O
Molecular Formula
C21H30N2O5S
Molecular Weight
422.54
References & Citations
[1]B Yee, et al., O013 Preliminary Results from a Phase 1 Study of ALKS 2680, an Orexin-2 receptor Agonist, in Healthy Participants and Patients with Narcolepsy or Idiopathic Hypersomnia.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172412/Alixorexton-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
OX2 Receptor
CAS Number
[2648347-56-0]
Available Sizes
Curated Selection
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