GLP-1R agonist 29
GLP-1R agonist 29 (Compound 20) is the agonist for GLP-1R that induces hGLP-1R mediated cAMP stimulation with an EC50 of 0.018 nM. GLP-1R agonist 29 exhibits good pharmacokinetics characteristics with good body exposure of AUC0-∞, sc of 77688 ng·h/mL[1].
Product Specifications
UNSPSC
12352005
Target
GLP Receptor
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Smiles
CC1=C(F)C(C)=CC(N2C(N3C=CN(C4=CC=C(N(C5CCC5)N=C6)C6=C4F)C3=O)=C7[C@H](C)N(C(C8=CC9=NC(C%10CCOCC%10)=CC=C9N8[C@@]%11(C%12=NOC(N%12)=O)C[C@@H]%11C)=O)CCC7=N2)=C1
Molecular Formula
C48H47F2N11O5
Molecular Weight
895.95
References & Citations
[1]Liang B, et al., GLP-1R agonist and therapeutic method thereof. US12234236
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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