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E3 Ligase Ligand-linker Conjugate 170

E3 Ligase Ligand-linker Conjugate 170 (Compound I) exhibits anti-proliferative activity in non-Hodgkin's lymphoma cell SU-DHL-4 with IC50 [1].

Product Specifications

CAS Number

[2379572-21-9]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1N(C2C(NC(CC2)=O)=O)C(C3=C(NCC4=CC=C(CN5CC(N6CCOCC6)C5)C=C4F)C=CC=C31)=O

Molecular Formula

C28H30FN5O5

Molecular Weight

535.57

References & Citations

[1]Anton MSC, et al., Methods of treating non-hodgkin lymphoma using 2- (2,6-dioxopiperidin-3-yl) -4- ((2-fluoro-4- ((3-morpholinoazetidin-1-yl) methyl) benzyl) amino) isoindoline-1,3-dione. WO2020210418A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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