Thalidomide-NH-C4-Boc
Thalidomide-NH-C4-Boc is the conjugate composed of an E3 ligase (Cereblon) ligand and a linker that can be used for synthesis of PROTAC CARM1/IKZF3 degrader-1.
Product Specifications
CAS Number
2226139-38-2
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1N(C2C(NC(CC2)=O)=O)C(C3=C(NCCCCCC(OC(C)(C)C)=O)C=CC=C31)=O
Molecular Formula
C23H29N3O6
Molecular Weight
443.49
References & Citations
[1]Ni W, et al. Dual CARM1-and IKZF3-targeting: a novel approach to multiple myeloma therapy Synergy between CARM1 inhibition and IMiDs[J]. Molecular Therapy Oncology, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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