CARM1/IKZF3 ligand 1
CARM1/IKZF3 ligand 1 is the inhibitor for CARM1 that can be used as the target protein ligand for synthesis of PROTAC CARM1/IKZF3 degrader-1 (HY-172368) [1].
Product Specifications
UNSPSC
12352005
Target
Histone Methyltransferase; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
ClC1=C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5(CCNCC5)C4)=N2)C=C(OC[C@@H](CNC)O)C=C1
Molecular Formula
C27H35ClN6O3
Molecular Weight
527.06
References & Citations
[1]Ni W, et al. Dual CARM1-and IKZF3-targeting: a novel approach to multiple myeloma therapy Synergy between CARM1 inhibition and IMiDs[J]. Molecular Therapy Oncology, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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