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CARM1/IKZF3 ligand 1

CARM1/IKZF3 ligand 1 is the inhibitor for CARM1 that can be used as the target protein ligand for synthesis of PROTAC CARM1/IKZF3 degrader-1 (HY-172368) [1].

Product Specifications

UNSPSC

12352005

Target

Histone Methyltransferase; Ligands for Target Protein for PROTAC

Related Pathways

Epigenetics; PROTAC

Field of Research

Cancer

Smiles

ClC1=C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5(CCNCC5)C4)=N2)C=C(OC[C@@H](CNC)O)C=C1

Molecular Formula

C27H35ClN6O3

Molecular Weight

527.06

References & Citations

[1]Ni W, et al. Dual CARM1-and IKZF3-targeting: a novel approach to multiple myeloma therapy Synergy between CARM1 inhibition and IMiDs[J]. Molecular Therapy Oncology, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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