JNJ-2901
JNJ-2901 is an inhibitor of M. tuberculosis cytochrome bc1:aa3. JNJ-2901 reduces bacterial load in the acute/chronic mouse infection models of M. tuberculosis H37Rv-ΔcydAB. JNJ-2901 can be used in tuberculosis (TB) research[1].
Product Specifications
CAS Number
[2059985-55-4]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CCC1=C(N2C=C(C=CC2=N1)Cl)C(NCC3=CC=C(C=C3)C4CC5(CN(C5)S(=O)(C(F)(F)F)=O)C4)=O
Molecular Formula
C24H24ClF3N4O3S
Molecular Weight
540.99
References & Citations
[1]Verma AK, et al. Structural and mechanistic study of a novel inhibitor analogue of M. tuberculosis cytochrome bc1:aa3. NPJ Drug Discov. 2025;2 (1) :6. doi: 10.1038/s44386-025-00008-3. Epub 2025 Apr 2. PMID: 40191462; PMCID: PMC11964921.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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