BRD-9327
BRD-9327 is an inhibitor of EfpA. BRD-9327 binds in the outer vestibule without complete blockade of the substrate path to the outside, suggesting its possible inhibition of the movement necessary for alternate access of the transporter. BRD-9327 can be used for anti-tuberculosis study[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(C1=CC=CCC1Br)NC2=CC3=C(OCCO3)C=C2C(C4=CC=CC=C4)=O
Molecular Formula
C22H18BrNO4
Molecular Weight
440.29
References & Citations
[1]Khandelwal NK, et al. Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A. Nat Commun. 2025 Apr 1;16 (1) :3139.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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