MitoA (bromide)

MitoA (bromide) is a mitochondria-targeted H2S probe, which can be used to assess relative changes in mitochondrial levels of H2S in vivo. MitoA (bromide) can accumulate inside mitochondria within tissues in vivo due to tryphenylphosphonium (TPP) cation. MitoA (bromide) can be studied in research on myocardial ischemia[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Cardiovascular Disease

Smiles

O=C(NCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C=C4)N=[N+]=[N-].[Br-]

Molecular Formula

C28H26BrN4OP

Molecular Weight

545.41

References & Citations

[1]Arndt S, et al., Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA. J Biol Chem. 2017 May 12;292 (19) :7761-7773.