HCy-Lyso
HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm[1][2].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
CC1(C(N(C2=CC=CC=C12)CC)/C=C/C3=CC=C(N4CCOCC4)C=C3)C
Molecular Formula
C24H30N2O
Molecular Weight
362.51
References & Citations
[1]Ransdell-Green EC, et al. Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes. Antioxidants (Basel) . 2025 Jan 10;14 (1) :79. |[2]Zhong L, et al. Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways. RSC Adv. 2024 Apr 22;14 (18) :12864-12872.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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