Q1-ALC-0315 (iodide)
Q1-ALC-0315 iodide is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid ALC-0315 (HY-138170) . Q1-ALC-0315-based LNPs can be used for lung-targeted mRNA delivery, which demonstrates high-performing firefly luciferase protein expression in the lungs[1].
Product Specifications
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Smiles
OCCCC[N+](C)(CCCCCCOC(C(CCCCCCCC)CCCCCC)=O)CCCCCCOC(C(CCCCCCCC)CCCCCC)=O.[I-]
Molecular Formula
C49H98INO5
Molecular Weight
908.21
References & Citations
[1]Zeng G, et al. Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery. ACS Appl Mater Interfaces. 2024 May 22;16 (20) :25698-25709.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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