BMS-986238
BMS-986238, a second-generation macrocyclic peptide, is a potent PD-L1 inhibitor. BMS-986238 has the potential for the study of solid tumours and lymphomas (cancer of the lymphatic system) [1].
Product Specifications
CAS Number
[2919596-13-5]
UNSPSC
12352209
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CN1C2=CC=CC=C2C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@](C[C@H]3O)([H])N(C3)C([C@@H](NC([C@@H](NC([C@@](CCC4)([H])N4C([C@@H](N5)CC(N)=O)=O)=O)CN)=O)CC(C)C)=O)=O)CC6=CNC7=CC=CC=C67)=O)CCN)=O)C(N([C@H](C(N([C@H](C(N[C@H](C(N[C@@H](CSCC(N[C@H](C(N([C@H](C5=O)C)C)=O)CC(C=C8)=CC=C8O)=O)C(NCC(N[C@H](C(O)=O)CC(N=N9)=CN9CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)CCCC)C)=O)CCCC)C)=O)=C1)=O
Molecular Formula
C143H224N26O40S
Molecular Weight
2979.52
References & Citations
[1]Discovery of BMS-986238, a second-generation macrocyclic peptide inhibitor of programmed death-ligand 1 (PD-L1) .
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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