IAMA-6
IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS) ), autism spectrum disorders (ASD) and Down syndrome (DoS) [1].
Product Specifications
UNSPSC
12352005
Target
NKCC
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(S(=O)(C1=CC(C(O)=O)=CC=C1NCCCCCCCC(F)(F)F)=O)C
Molecular Formula
C17H25F3N2O4S
Molecular Weight
410.45
References & Citations
[1]Annalisa Savardi, et al. Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with Defective NKCC1/KCC2 expression-ratio (P2-12.003) . April 25, 2023 issue 100 (17_supplement_2) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172318/IAMA-6-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
CAS Number
[2497525-96-7]
Available Sizes
Curated Selection
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