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IAMA-6

IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS) ), autism spectrum disorders (ASD) and Down syndrome (DoS) [1].

Product Specifications

CAS Number

2497525-96-7

UNSPSC

12352005

Target

NKCC

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(S(=O)(C1=CC(C(O)=O)=CC=C1NCCCCCCCC(F)(F)F)=O)C

Molecular Formula

C17H25F3N2O4S

Molecular Weight

410.45

References & Citations

[1]Annalisa Savardi, et al. Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with Defective NKCC1/KCC2 expression-ratio (P2-12.003) . April 25, 2023 issue 100 (17_supplement_2) .

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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