DSPE-PEG5000-Cys-SRNLIDC (Disulfide bridge: Cys1-Cys8)

DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB) . pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC) . DSPE-PEG5000-pPB can be used for drug delivery[1].

Product Specifications

UNSPSC

12352200

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

[Cys-SRNLIDC(Disulfidebridge:Cys1-Cys8)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

Molecular Weight

5000 (Average)

References & Citations

[1]Jia Z, et al. pPB Peptide-Mediated siRNA-Loaded Stable Nucleic Acid Lipid Nanoparticles on Targeting Therapy of Hepatic Fibrosis. Mol Pharm. 2018 Jan 2;15 (1) :53-62.