DSPE-PEG5000-Cys-SRNLIDC (Disulfide bridge: Cys1-Cys8)
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB) . pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC) . DSPE-PEG5000-pPB can be used for drug delivery[1].
Product Specifications
UNSPSC
12352200
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
[Cys-SRNLIDC(Disulfidebridge:Cys1-Cys8)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
Molecular Weight
5000 (Average)
References & Citations
[1]Jia Z, et al. pPB Peptide-Mediated siRNA-Loaded Stable Nucleic Acid Lipid Nanoparticles on Targeting Therapy of Hepatic Fibrosis. Mol Pharm. 2018 Jan 2;15 (1) :53-62.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
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