DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY

DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep) . M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery[1].

Product Specifications

UNSPSC

12352200

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[Mal-Cys-YEQDPWGVKWWY]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

Molecular Weight

5000 (Average)

References & Citations

[1]Pang L, et al. Surface Modification of Polymeric Nanoparticles with M2pep Peptide for Drug Delivery to Tumor-Associated Macrophages. Pharm Res. 2019 Mar 11;36 (4) :65.