STG-001

STG-001 is a retinol binding protein 4 (RBP4) antagonist. STG-001 inhibits RBP4 to reduce the synthesis of retinal and diretinol, thereby preventing photoreceptor degeneration. STG-001 can be used in the study of sexually precocious nephropathy (STGD) [1].

Product Specifications

CAS Number

[1911650-53-7]

UNSPSC

12352005

Target

Lipocalin Family

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

O=C(CCN1N=C(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=C1)O

Molecular Formula

C14H10F6N2O2

Molecular Weight

352.23

References & Citations

[1]Kim N, et al. Retinol binding protein 4 antagonists and protein synthesis inhibitors: Potential for therapeutic development. Eur J Med Chem. 2021 Dec 15;226:113856.