S-15176
S-15176 is an inhibitor of the mitochondrial permeability transition pore (PTP) . S-15176 inhibits mitochondrial swelling induced by tert-butylhydroperoxide with an IC50 value of 45.7 μM. S-15176 inhibits PTP opening, prevents mitochondrial membrane potential dissipation and NAD (P) H oxidation, and increases mitochondrial calcium loading capacity. S-15176 is promising for research of ischemia-reperfusion injury[1][2].
Product Specifications
UNSPSC
12352005
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
OC1=C(C(C)(C)C)C=C(SCCCN2CCN(CC2)CC3=CC=C(C(OC)=C3OC)OC)C=C1C(C)(C)C
Molecular Formula
C31H48N2O4S
Molecular Weight
544.79
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172227/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[148089-70-7]
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