3-Deazaguanosine

3-Deazaguanosine (C3Guo) has potent antiviral activity against SARS-CoV-2 (EC50: 1.14 μM, CC50: >200 μM for Vero E6 cells) . 3-Deazaguanosine prevents COVID-19 pneumonia[1].

Product Specifications

CAS Number

[56039-11-3]

Product Name Alternative

C3Guo

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2C=C(N)NC3=O)O[C@@H]1CO

Molecular Formula

C11H14N4O5

Molecular Weight

282.25

References & Citations

[1]Saito-Tarashima N, et al. 3-Deazaguanosine inhibits SARS-CoV-2 viral replication and reduces the risk of COVID-19 pneumonia in hamster. iScience. 2025 Mar 1;28 (4) :112140.