ChlaDUB1-IN-2
ChlaDUB1-IN-2 (Compound 27a) is the inhibitor for Chlamydia trachomatis deubiquitinase ChlaDUB1 with an IC50 of 0.97 μM. ChlaDUB1-IN-2 inhibits the inclusion body formation of C. trachomatis with an IIC50 of 25.6 μg/mL[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Deubiquitinase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C(N1N=C(C2=C1C=CC=C2)CNC(C3=NC(C#N)=NC=C3)=O)CC4=CC=CC=C4
Molecular Formula
C22H16N6O2
Molecular Weight
396.40
References & Citations
[1]Zimmermann T, et al., Structural Optimization of Covalent Inhibitors for Deubiquitinase ChlaDUB1 of Chlamydia trachomatis as Antibiotic Agents. J Med Chem. 2025 Mar 13;68 (5) :5400-5425.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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