CUR-IPA

CUR-IPA is a cholinesterase inhibitor, with IC50 of 5.99, 59.30, and 60.66 μM for eAChE (electric eel), hAChE (human), and hBChE (human), respectively. CUR-IPA can scavenge free radicals and has antioxidant activity. CUR-IPA can be used in the research of cognitive dysfunction[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

COC1=CC(/C=C/C(CC(/C=C/C2=CC=C(C(OC)=C2)OC(CCC3=CNC4=C3C=CC=C4)=O)=O)=O)=CC=C1OC(CCC5=CNC6=C5C=CC=C6)=O

Molecular Formula

C43H38N2O8

Molecular Weight

710.77

References & Citations

[1]Sidhambaram J, et al. Esterified Indole-3-propionic Acid: A Novel Inhibitor against Cholinesterase Identified through Experimental and Computational Approaches. ACS Omega. 2025 Mar 1;10 (9) :9073-9087.